Gene Silencing Breakthrough Raises Hope for ALS Treatment
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Contributed by Ron Gara| 14 March, 2005 20:42 GMT
Swiss scientists have succeeded in silencing the genetic mutation that causes inherited cases of amytrophic lateral sclerosis (ALS), also known as "Lou Gehrig's disease," in experiments conducted with mice. Experiments using RNA interference in transgenic mice (mice bred to express the human ALS gene) substantially delayed both the onset and the progression rate of the fatal motor neuron disease.
Results of the research, which was carried out at the Ecole Polytechnique F |
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